
Fetal skeleton showing traits of osteogenesis imperfecta type II. Type II is the most severe form of OI. At birth, infants with OI Type II have very short limbs, small chests, and soft skulls. Their legs are often in a frog-leg position. The radiologic features are characteristic and include absent or limited calvarial mineralization; flat vertebral bodies; very short, telescoped, broad femurs; beaded and often broad short ribs; and evidence of malformation of the long bones.